SCHEMBL357440

SCHEMBL357440

C#CCc1cccc(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.54
DRD2 P14416 3/20 0.50
DRD1 P21728 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
CYP3A4 P08684 2/20 0.48
CYP1A2 P05177 1/20 0.48
PKM P14618 1/20 0.48
ALOX15 P16050 1/20 0.48
NFKB1 P19838 1/20 0.48
MAPK1 P28482 1/20 0.48
LMNA P02545 2/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
CA12 O43570 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9350384 0.84 MEN1 (0.41) ENPP2CYP3A4CYP1A2LMNAKMT2A
SCHEMBL19609051 0.82 ENPP2 (0.58) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL30737423 0.79 DRD2 (0.57) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL1233598 0.78 MMP3 (0.65) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL3689366 0.78 ENPP2 (0.45) ENPP2
SCHEMBL7773782 0.78 MIF (0.55) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL9508918 0.78 ENPP2 (0.54) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL909770 0.78 DRD2 (0.55) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL2809012 0.75 ENPP2 (0.50) ENPP2DRD2DRD1TAAR1CYP3A4
Resorcinol SCHEMBL18335395 0.75 ALDH1A1 (0.60) ENPP2DRD2DRD1TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1689816-B1 CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF DOW CORNING TORAY CO LTD (JP) 2010-07-14 EP claimed
EP-0922050-B1 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES ABBOTT LAB (US) 2003-07-30 EP claimed
EP-0475437-B1 Organocyclosiloxane and method for its preparation DOW CORNING TORAY SILICONE (JP) 1995-11-08 EP claimed
US-11901249-B2 Curable composition and cured product thereof DIC CORPORATION (JP) 2024-02-13 US disclosed
CN-112119104-B Epoxy (meth) acrylate resin composition, curable resin composition, cured product, and article DIC株式会社 2023-09-29 CN disclosed
CN-111918891-B Curable composition and cured product thereof DIC株式会社 2023-02-28 CN disclosed
CN-112105661-B Acid group-containing (meth) acrylate resin composition, curable resin composition, cured product, and resin material for solder resist DIC株式会社 2023-02-24 CN disclosed
US-11548977-B2 Active ester resin and composition and cured product using the same DIC CORPORATION (JP) 2023-01-10 US disclosed
CN-110770202-B Active ester resin, and composition and cured product using same DIC株式会社 2022-12-16 CN disclosed
US-20210009804-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF DIC CORPORATION (JP) 2021-01-14 US disclosed
CN-112119104-A Epoxy (meth) acrylate resin composition, curable resin composition, cured product, and article DIC株式会社 2020-12-22 CN disclosed
CN-1354166-A Process for preparing cyclopropane carboxylic acid ester SUMITOMO CHEMICAL CO (JP) 2002-06-19 CN disclosed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed
CN-1282729-A Preparation method of cyclopropane carboxylic acid ester SUMITOMO CHEMICAL CO (JP) 2001-02-07 CN disclosed
EP-1061065-A2 Methods for producing cyclopropane carboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-20 EP disclosed
CN-1255489-A Method for preparing cyclopropane carboxylic ester SUMITOMO CHEM ENG (JP) 2000-06-07 CN disclosed
EP-0992479-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-12 EP disclosed
CN-87103507-A The preparation of propargyl oxybenzene derivative and contain the mycocide of propargyl oxybenzene derivative 1988-01-13 CN disclosed
EP-0183212-A2 Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 ENPP2 3485/4885DRD2 645/4885DRD1 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.