Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510305 | 0.84 | ALDH1A1 (0.51) | ALDH1A1USP2LMNAGFERTSHR | |
| SCHEMBL9509233 | 0.81 | ALDH1A1 (0.53) | ALDH1A1USP2LMNAGFERTSHR | |
| SCHEMBL9509209 | 0.80 | GAA (0.36) | ALDH1A1LMNATSHRCYP2C9CYP2C19 | |
| SCHEMBL417273 | 0.75 | ALDH1A1 (0.53) | ALDH1A1USP2LMNAGFERTSHR | |
| SCHEMBL9512549 | 0.73 | ALDH1A1 (0.65) | ALDH1A1USP2LMNAGFERTSHR | |
| SCHEMBL9509754 | 0.72 | KMT2A (0.53) | ALDH1A1LMNATSHRMEN1MAPT | |
| SCHEMBL9510270 | 0.72 | HPN (0.44) | ALDH1A1LMNARECQLTSHRMAPT | |
| SCHEMBL9483866 | 0.72 | MEN1 (0.46) | ALDH1A1LMNARECQLMEN1MAPT | |
| SCHEMBL9550708 | 0.70 | HPN (0.47) | ALDH1A1LMNARECQLMAPTKMT2A | |
| SCHEMBL8309788 | 0.70 | VCAM1 (0.55) | ALDH1A1LMNARECQLMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372409-B1 | Acylaminoalkylpyridineamides as inhibitors of tumor metastasis | SEARLE & CO (US) | 1993-10-27 | — | — | EP | claimed |
| EP-0190683-B1 | NOVEL AMINOALKYLPYRDINEAMIDES | G.D. Searle & Co. (US) | 1992-09-16 | — | — | EP | claimed |
| US-5030642-A | Antitumor agents | G. D. SEARLE & CO. (US) | 1991-07-09 | — | — | US | claimed |
| EP-0372409-A2 | Acylaminoalkylpyridineamides as inhibitors of tumor metastasis | G.D. Searle & Co. (US) | 1990-06-13 | — | — | EP | claimed |
| EP-0372409-B1 | Acylaminoalkylpyridineamides as inhibitors of tumor metastasis | SEARLE & CO (US) | 1993-10-27 | — | — | EP | disclosed |
| EP-0190683-B1 | NOVEL AMINOALKYLPYRDINEAMIDES | G.D. Searle & Co. (US) | 1992-09-16 | — | — | EP | disclosed |
| US-5030642-A | Antitumor agents | G. D. SEARLE & CO. (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0372409-A2 | Acylaminoalkylpyridineamides as inhibitors of tumor metastasis | G.D. Searle & Co. (US) | 1990-06-13 | — | — | EP | disclosed |
| US-4663333-A | Acylaminoalkylpyridines ad use in treatment of inflammation and allergy reactions | G. D. SEARLE & CO. (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0190683-A2 | Novel aminoalkylpyrdineamides | G.D. Searle & Co. (US) | 1986-08-13 | — | — | EP | disclosed |