Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748554 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNAHTTCYP1A2CYP2C19 | |
| SCHEMBL28220083 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTCYP1A2CYP2C19 | |
| SCHEMBL11202452 | 0.82 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTCYP1A2CYP2C19 | |
| SCHEMBL2345502 | 0.78 | HPGD (0.54) | ALDH1A1LMNAHTTCYP1A2CYP2C19 | |
| SCHEMBL1077703 | 0.75 | MAPT (0.49) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| SCHEMBL9505790 | 0.74 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTCYP2C19CYP3A4 | |
| SCHEMBL12387069 | 0.74 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTCYP1A2CYP2C19 | |
| SCHEMBL2512529 | 0.74 | MAPT (0.57) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| SCHEMBL15085181 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTCYP1A2CYP2C19 | |
| SCHEMBL16656576 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5004812-A | Phenyl-pyridyl-indole Intermediates For Desensitizing Dyes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| US-4927933-A | PHOTOGRAPHIC FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4839271-A | SENSITIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |