Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28220083 | 0.90 | ALDH1A1 (0.52) | ALDH1A1LMNAIL1R1L3MBTL1KMT2A | |
| SCHEMBL9509638 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL9505790 | 0.86 | ALDH1A1 (0.49) | ALDH1A1LMNAIL1R1L3MBTL1KMT2A | |
| SCHEMBL9505772 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAIL1R1L3MBTL1KMT2A | |
| SCHEMBL18803008 | 0.78 | IL1R1 (0.62) | ALDH1A1LMNAIL1R1L3MBTL1KMT2A | |
| SCHEMBL2343158 | 0.78 | KDM4E (0.52) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL1429358 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1MAPTHTT | |
| SCHEMBL29954953 | 0.78 | KDM4E (0.52) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL22443301 | 0.78 | L3MBTL1 (0.52) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL29822336 | 0.77 | IL1R1 (0.60) | ALDH1A1LMNAIL1R1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-6706423-B2 | Organic EL device | LIGHTRONIK TECHNOLOGY INC. (TW) | 2004-03-16 | — | — | US | disclosed |
| US-20030165712-A1 | Organic EL Device | LIGHTRONIK TECHNOLOGY INC. (TW) | 2003-09-04 | — | — | US | disclosed |
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5004812-A | Phenyl-pyridyl-indole Intermediates For Desensitizing Dyes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| US-4927933-A | PHOTOGRAPHIC FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4839271-A | SENSITIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0296873-A2 | Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |