Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748554 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7811410 | 0.81 | LMNA (0.71) | ALDH1A1LMNACYP11B2MAPTTBXAS1 | |
| SCHEMBL1606149 | 0.78 | CYP11B2 (0.48) | ALDH1A1LMNACYP11B2MAPTMEN1 | |
| SCHEMBL28220083 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9509638 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL23057379 | 0.71 | L3MBTL1 (0.51) | ALDH1A1LMNACYP11B2MAPTMEN1 | |
| SCHEMBL28917737 | 0.71 | L3MBTL1 (0.47) | ALDH1A1CYP11B2MAPTMEN1KMT2A | |
| SCHEMBL16484609 | 0.71 | CYP2A6 (0.50) | ALDH1A1CYP11B2CYP3A4CYP2A6L3MBTL1 | |
| SCHEMBL12091849 | 0.71 | AGTR1 (0.53) | ALDH1A1CYP11B2MAPTMEN1KMT2A | |
| SCHEMBL9505772 | 0.70 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| US-5004812-A | Phenyl-pyridyl-indole Intermediates For Desensitizing Dyes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-02 | — | — | US | claimed |
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5004812-A | Phenyl-pyridyl-indole Intermediates For Desensitizing Dyes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| US-4927933-A | PHOTOGRAPHIC FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4839271-A | SENSITIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0296873-A2 | Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |