Styrene

Styrene

SCHEMBL9509768

C=C(CC)C(=O)OC(=C)C(=O)OCC.C=C(CC)C(=O)OCCCCCC.C=Cc1ccccc1

nearest known ligand 0.41

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 4/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 3/20 0.40
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 1/20 0.37
KDM4E B2RXH2 2/20 0.37
POLB P06746 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PPARG P37231 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL491216 0.91 TSHR (0.48) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL10533310 0.88 TSHR (0.45) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL9718413 0.86 HCAR2 (0.48) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL11208181 0.85 TSHR (0.56) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL9510293 0.85 TSHR (0.44) MEN1KMT2ATSHRALDH1A1LMNA
Styrene SCHEMBL7213574 0.84 TSHR (0.50) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL6343507 0.84 TSHR (0.42) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL4146543 0.83 TSHR (0.50) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL6709068 0.83 TSHR (0.47) TSHRALDH1A1LMNATP53CYP3A4
Styrene SCHEMBL11607106 0.83 KDM4E (0.44) MEN1KMT2ATSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315702-B1 THERMOSETTING WATER PAINT COMPOSITION NIPPON PAINT CO., LTD. (JP) 1993-10-06 EP disclosed
EP-0315702-A1 THERMOSETTING WATER PAINT COMPOSITION NIPPON PAINT CO., LTD. (JP) 1989-05-17 EP disclosed