SCHEMBL9509819

SCHEMBL9509819

COP(=O)(O)C(CO)P(=O)(O)OC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.37
FDPS P14324 3/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP8 P22894 1/20 0.33
CA9 Q16790 1/20 0.33
CYP2C19 P33261 1/20 0.30
ANPEP P15144 1/20 0.30
PPARD Q03181 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9512992 0.90 FDPS (0.41) LAP3FDPSCA12CA1CA2
SCHEMBL5897537 0.75 FDPS (0.41) LAP3FDPSCA12CA1CA2
SCHEMBL6900096 0.73 LAP3 (0.34) LAP3CYP2C19LMNA
SCHEMBL9509135 0.72 FDPS (0.48) LAP3FDPS
SCHEMBL28362509 0.72 FDPS (0.67) LAP3FDPS
SCHEMBL9250575 0.70 FDPS (0.37) LAP3FDPS
SCHEMBL12873310 0.69
Phosphoric Acid Monomethyl Ester SCHEMBL19453204 0.68 LMNA (0.47) FDPSCYP2C19LMNA
E968 SCHEMBL1488998 0.68 LMNA (0.36) FDPSCYP2C19LMNA
SCHEMBL3904202 0.67 FDPS (0.48) LAP3FDPSMMP2ANPEPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563096-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 1993-10-06 EP disclosed