Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957190 | 0.91 | TP53 (0.38) | TP53ADORA3ADORA2AADORA1DRD2 | |
| SCHEMBL7056477 | 0.91 | TP53 (0.46) | TP53ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL7056482 | 0.91 | TP53 (0.46) | TP53ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL8957161 | 0.84 | TP53 (0.40) | TP53ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL9508507 | 0.84 | TP53 (0.36) | TP53ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL8957023 | 0.81 | TP53 (0.45) | TP53ALDH1A1HSD17B10 | |
| SCHEMBL8957028 | 0.81 | TP53 (0.45) | TP53ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9530574 | 0.80 | MAPT (0.41) | TP53ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL8954186 | 0.79 | TP53 (0.46) | TP53ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL9507591 | 0.79 | FNTA (0.39) | TP53ADORA3ADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561905-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF MACULAR DEGENERATION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561896-A1 | USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |