Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509874 | 0.89 | LMNA (0.50) | CYP1A2ACE2FAAHCNR1CNR2 | |
| SCHEMBL9509850 | 0.87 | LMNA (0.58) | CYP1A2ACE2FAAHCNR1CNR2 | |
| SCHEMBL9509877 | 0.86 | LMNA (0.61) | CYP1A2ACE2FAAHCNR1CNR2 | |
| SCHEMBL9507450 | 0.86 | LMNA (0.61) | CYP1A2ACE2FAAHCNR1CNR2 | |
| SCHEMBL9703061 | 0.86 | LMNA (0.61) | CYP1A2ACE2FAAHCNR1CNR2 | |
| SCHEMBL9508041 | 0.84 | GABRR1 (0.45) | CYP1A2ACE2FAAHCNR1CNR2 | |
| SCHEMBL3099673 | 0.84 | ALDH1A1 (0.48) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9447620 | 0.84 | ALDH1A1 (0.48) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL9508739 | 0.82 | FAAH (0.44) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL10900230 | 0.80 | FAAH (0.53) | FAAHCNR1CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |