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Serine

Serine

SCHEMBL9509964

CC[C@H](C)[C@H](N)C(=O)OC(=O)CN.N=C(N)NCCC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1ccc(OC(=O)CN)cc1.N[C@@H](CO)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.38
▸ NPY1R P25929 7/20 0.38
▸ NPY2R P49146 5/20 0.37
▸ NPY5R Q15761 5/20 0.37
▸ SLC7A5 Q01650 1/20 0.33
▸ ITGB3 P05106 1/20 0.32
▸ ITGA2B P08514 1/20 0.32
▸ GRB2 P62993 2/20 0.31
▸ KISS1R Q969F8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL675717 0.92 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RSLC7A5
Serine SCHEMBL15752146 0.91 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RSLC7A5
SCHEMBL2674971 0.88 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RSLC7A5
Serine SCHEMBL8169168 0.88 NPY4R (0.32) NPY4RNPY1RNPY2RNPY5RSLC7A5
Glycine SCHEMBL5344900 0.86 NPY4R (0.38) NPY4RNPY1RNPY2RNPY5RSLC7A5
Proline SCHEMBL9512840 0.85 NPY4R (0.31) NPY4RNPY1RNPY2RNPY5R
SCHEMBL995485 0.85 NPY4R (0.36) NPY4RNPY1RNPY2RNPY5RSLC7A5
Serine SCHEMBL9512908 0.84 NPY4R (0.40) NPY4RNPY1RNPY2RNPY5RSLC7A5
Arginine SCHEMBL4405153 0.83 NPY4R (0.36) NPY4RNPY1RNPY2RNPY5RSLC7A5
Proline SCHEMBL3087442 0.83 MAPK8 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0278781-B1 Peptides with laminin activity US COMMERCE (US) 1993-11-03 — — EP claimed
US-5092885-A Antitumor agents, wouond healing agents, promoters of cell adhesion to prostheses THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1992-03-03 — — US claimed
WO-1988006039-A1 PEPTIDES WITH LAMININ ACTIVITY UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) 1988-08-25 — — WO claimed