Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.48 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131688 | 0.84 | MEN1 (0.54) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL1275610 | 0.82 | CYP1A2 (0.56) | MEN1KMT2ACYP3A4HIF1ATSHR | |
| SCHEMBL22898034 | 0.82 | MEN1 (0.47) | MEN1KMT2ACYP3A4HPGDTSHR | |
| SCHEMBL3513523 | 0.81 | SNCA (0.54) | KMT2ATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL27570737 | 0.81 | ALOX5 (0.53) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL13120858 | 0.80 | MEN1 (0.50) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL10774333 | 0.80 | CYP3A4 (0.44) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL29274282 | 0.80 | NPC1 (0.61) | MEN1KMT2ACYP3A4HPGDHSD17B10 | |
| SCHEMBL40607 | 0.79 | ALDH1A1 (0.60) | MEN1KMT2AHPGDHSD17B10TSHR | |
| SCHEMBL1750770 | 0.79 | PKM (0.58) | MEN1KMT2ATSHRMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268849-B1 | Poly(aminoaromatic) compounds | DOW CHEMICAL CO (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5079275-A | Polyamino compound is an amino endcapped polyether, polyester, polycarbonate, resole, hydroxybutadiene | THE DOW CHEMICAL COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| US-4847416-A | Capping of polyols with aromatic amines | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0268849-A2 | Poly(aminoaromatic) compounds | THE DOW CHEMICAL COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |