Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506940 | 0.83 | TBXA2R (0.53) | TBXA2RTBXAS1RCE1 | |
| SCHEMBL7832985 | 0.80 | HDAC1 (0.54) | RCE1 | |
| SCHEMBL67664 | 0.77 | TBXA2R (0.65) | TBXA2RTBXAS1CYP2D6RAB9A | |
| SCHEMBL7833010 | 0.77 | TNF (0.46) | TBXA2RCYP2D6CYP2C19RCE1NPC1 | |
| SCHEMBL67079 | 0.73 | TBXA2R (0.58) | TBXA2RTBXAS1CYP2D6RAB9A | |
| SCHEMBL8742992 | 0.72 | TBXA2R (0.58) | TBXA2R | |
| SCHEMBL8743003 | 0.72 | TBXA2R (0.58) | TBXA2R | |
| SCHEMBL7683666 | 0.71 | TBXAS1 (0.73) | TBXA2RTBXAS1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7773626 | 0.71 | TBXAS1 (0.73) | TBXA2RTBXAS1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3154532 | 0.69 | TBXAS1 (0.71) | TBXA2RTBXAS1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |