Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510689 | 0.83 | TBXA2R (0.56) | TBXA2RTBXAS1RCE1 | |
| SCHEMBL67664 | 0.75 | TBXA2R (0.65) | TBXA2RTBXAS1SLC6A3CACNA1FDRD4 | |
| SCHEMBL9699510 | 0.70 | TBXA2R (0.82) | TBXA2RTBXAS1KCNH2SLC6A3 | |
| SCHEMBL67079 | 0.70 | TBXA2R (0.58) | TBXA2RTBXAS1SLC6A3CACNA1FDRD4 | |
| SCHEMBL8742992 | 0.69 | TBXA2R (0.58) | TBXA2RLTB4R | |
| SCHEMBL8743003 | 0.69 | TBXA2R (0.58) | TBXA2RLTB4R | |
| SCHEMBL8743193 | 0.69 | TBXA2R (0.76) | TBXA2RTBXAS1KCNH2SLC6A3HTR2A | |
| SCHEMBL9507218 | 0.69 | TBXA2R (0.76) | TBXA2RTBXAS1KCNH2SLC6A3HTR2A | |
| SCHEMBL8743182 | 0.69 | TBXA2R (0.76) | TBXA2RTBXAS1KCNH2SLC6A3HTR2A | |
| SCHEMBL7683666 | 0.69 | TBXAS1 (0.73) | TBXA2RTBXAS1SLC6A3HTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |