Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 2/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383607 | 0.75 | NCF1 (0.43) | TERTALDH1A1L3MBTL1NOS3NOS1 | |
| SCHEMBL9511107 | 0.75 | NOS2 (0.42) | TERTNOS3NOS1NOS2 | |
| SCHEMBL17085823 | 0.75 | — | — | |
| SCHEMBL280576 | 0.71 | NOS3 (0.34) | TERTALDH1A1L3MBTL1NOS3NOS1 | |
| SCHEMBL27385578 | 0.71 | TDP1 (0.39) | TERTCD44ALDH1A1L3MBTL1 | |
| SCHEMBL2905943 | 0.71 | — | — | |
| SCHEMBL14419253 | 0.68 | — | — | |
| SCHEMBL29839686 | 0.68 | NNMT (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL95213 | 0.68 | NNMT (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL30303130 | 0.67 | HSP90AA1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566698-A1 | AMINO-SUBSTITUTED PYRIMIDINES, DERIVATIVES AND METHODS OF USE THEREFOR | THE ROCKEFELLER UNIVERSITY (US) | 1993-10-27 | — | — | EP | disclosed |
| WO-1992011853-A1 | AMINO-SUBSTITUTED PYRIMIDINES, DERIVATIVES AND METHODS OF USE THEREFOR | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-23 | — | — | WO | disclosed |