Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512269 | 0.95 | HTR7 (0.60) | HTR7DRD2ALDH1A1DRD3MAPT | |
| SCHEMBL9511100 | 0.95 | HTR7 (0.60) | HTR7DRD2ALDH1A1DRD3MAPT | |
| SCHEMBL9512303 | 0.92 | KMT2A (0.62) | HTR7DRD2ALDH1A1DRD3KMT2A | |
| SCHEMBL9510088 | 0.92 | HTR7 (0.57) | HTR7DRD2ALDH1A1DRD3MAPT | |
| SCHEMBL12672472 | 0.88 | HTR7 (0.83) | HTR7DRD2ALDH1A1KMT2AHTR1A | |
| SCHEMBL10826588 | 0.86 | DRD2 (0.54) | DRD2ALDH1A1DRD3MAPTMAPK1 | |
| SCHEMBL5198457 | 0.82 | HTR7 (0.74) | HTR7ALDH1A1KMT2AHTR1ACCR1 | |
| SCHEMBL9510048 | 0.82 | HTR7 (0.51) | HTR7DRD2ALDH1A1DRD3MAPT | |
| SCHEMBL10722023 | 0.80 | HTR7 (0.71) | HTR7ALDH1A1MAPTKMT2AHTR1A | |
| SCHEMBL13045322 | 0.79 | KMT2A (0.76) | HTR7ALDH1A1KMT2ANPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330065-B1 | Sulfonamide compounds | KOWA CO (JP) | 1993-11-10 | — | — | EP | claimed |
| US-4948892-A | Sulfonamid compound useful for treating cardiovascular disorders | KOWA COMP., LTD. (JP) | 1990-08-14 | — | — | US | claimed |
| EP-0330065-A1 | Sulfonamide compounds | KOWA COMPANY, LTD. (JP) | 1989-08-30 | — | — | EP | claimed |
| JP-1211567-A | — | — | None | — | — | JP | disclosed |
| EP-0330065-B1 | Sulfonamide compounds | KOWA CO (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-4948892-A | Sulfonamid compound useful for treating cardiovascular disorders | KOWA COMP., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0330065-A1 | Sulfonamide compounds | KOWA COMPANY, LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |
| JP-H01211567-A | NOVEL SULFONAMIDE COMPOUND | KOWA CO | 1989-08-24 | — | — | JP | disclosed |