Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512269 | 1.00 | HTR7 (0.60) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9511082 | 0.95 | HTR7 (0.67) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9512303 | 0.87 | KMT2A (0.62) | HTR7DRD2HTR2AHTR6ALDH1A1 | |
| SCHEMBL9510088 | 0.87 | HTR7 (0.57) | HTR7DRD2HTR1AHTR2AALDH1A1 | |
| SCHEMBL12672472 | 0.83 | HTR7 (0.83) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL10826588 | 0.81 | DRD2 (0.54) | DRD2HTR2AALDH1A1LMNADRD3 | |
| SCHEMBL7389546 | 0.81 | ALDH1A1 (0.64) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL7391177 | 0.79 | HTR7 (0.65) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL7773443 | 0.79 | DRD2 (0.57) | DRD2ALDH1A1LMNADRD3L3MBTL1 | |
| SCHEMBL12373318 | 0.78 | DRD3 (0.59) | DRD2HTR2ADRD3ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330065-B1 | Sulfonamide compounds | KOWA CO (JP) | 1993-11-10 | — | — | EP | claimed |
| US-4948892-A | Sulfonamid compound useful for treating cardiovascular disorders | KOWA COMP., LTD. (JP) | 1990-08-14 | — | — | US | claimed |
| EP-0330065-A1 | Sulfonamide compounds | KOWA COMPANY, LTD. (JP) | 1989-08-30 | — | — | EP | claimed |