Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | CCR1 | P32246 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.56 |
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | HRH2 | P25021 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TEK | Q02763 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511082 | 0.92 | HTR7 (0.67) | KMT2AHTR7CCR1ALDH1A1DRD3 | |
| SCHEMBL9510088 | 0.89 | HTR7 (0.57) | KMT2AHTR7CCR1ALDH1A1DRD3 | |
| SCHEMBL9511100 | 0.87 | HTR7 (0.60) | KMT2AHTR7ALDH1A1DRD3DRD2 | |
| SCHEMBL9512269 | 0.87 | HTR7 (0.60) | KMT2AHTR7ALDH1A1DRD3DRD2 | |
| SCHEMBL10826588 | 0.81 | DRD2 (0.54) | KMT2AALDH1A1DRD3DRD2HTR2A | |
| SCHEMBL7670965 | 0.80 | DRD3 (0.72) | KMT2AHTR7ALDH1A1DRD3DRD2 | |
| SCHEMBL12672472 | 0.80 | HTR7 (0.83) | KMT2AHTR7CCR1ALDH1A1DRD2 | |
| SCHEMBL27679499 | 0.80 | ALDH1A1 (0.60) | KMT2AHTR7ALDH1A1GAADRD3 | |
| SCHEMBL29022589 | 0.79 | HTR1A (0.64) | KMT2AHTR7CCR1HTR2AHTR6 | |
| SCHEMBL7098325 | 0.78 | DRD3 (0.57) | HTR7DRD3DRD2HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330065-B1 | Sulfonamide compounds | KOWA CO (JP) | 1993-11-10 | — | — | EP | claimed |
| US-4948892-A | Sulfonamid compound useful for treating cardiovascular disorders | KOWA COMP., LTD. (JP) | 1990-08-14 | — | — | US | claimed |
| EP-0330065-A1 | Sulfonamide compounds | KOWA COMPANY, LTD. (JP) | 1989-08-30 | — | — | EP | claimed |