Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514131 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4ECHRNA1CHRNA7NPC1 | |
| SCHEMBL9511632 | 0.83 | HTT (0.59) | ALDH1A1KDM4EHTTPOLBKMT2A | |
| SCHEMBL4182979 | 0.82 | MAPK1 (0.57) | ALDH1A1KDM4EMAPK1POLBKMT2A | |
| SCHEMBL9512641 | 0.79 | POLB (0.62) | ALDH1A1MAPK1POLBGRM2KMT2A | |
| SCHEMBL9741850 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4ECHRNA1CHRNA7NPC1 | |
| SCHEMBL28958218 | 0.79 | POLB (0.56) | ALDH1A1CHRNA1CHRNA7NPC1HTT | |
| SCHEMBL9743824 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CHRNA1CHRNA7NPC1HTT | |
| SCHEMBL9511103 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4EHDAC1HDAC6POLB | |
| SCHEMBL14094206 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4ECHRNA1CHRNA7NPC1 | |
| SCHEMBL9413138 | 0.74 | MAPT (0.56) | ALDH1A1KDM4ENPC1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294719-B | Synthesis method of thiazolidone compound | 五邑大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114409680-A | PPAR agonist and application thereof | 上海怡立舍生物技术有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108250058-B | PPAR agonists and their use in the treatment of Alzheimer's disease and other diseases | 上海怡立舍生物技术有限公司 | 2022-02-11 | — | — | CN | disclosed |