Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158977 | 0.79 | NPC1 (0.66) | NPC1RAB9AHTTNTSR1KDM4E | |
| Perchlorate SCHEMBL9508583 | 0.78 | RAB9A (0.70) | NPC1RAB9AHTTNTSR1KDM4E | |
| Perchlorate SCHEMBL11536227 | 0.77 | NPC1 (1.00) | NPC1RAB9AHTTNTSR1KDM4E | |
| SCHEMBL14356289 | 0.76 | NPC1 (0.61) | NPC1RAB9AHTTNTSR1KDM4E | |
| SCHEMBL9512235 | 0.76 | RAB9A (0.61) | NPC1RAB9AHTTNTSR1KDM4E | |
| Hydrochloric Acid SCHEMBL23198666 | 0.74 | NPC1 (0.64) | NPC1RAB9AHTTNTSR1KDM4E | |
| SCHEMBL23198663 | 0.73 | CA2 (0.49) | NPC1RAB9AHTTNTSR1KDM4E | |
| SCHEMBL11533950 | 0.72 | NPC1 (0.84) | NPC1RAB9AHTTNTSR1KDM4E | |
| SCHEMBL805082 | 0.72 | NPC1 (0.77) | NPC1RAB9AHTTNTSR1KDM4E | |
| SCHEMBL23198667 | 0.72 | RAB9A (0.56) | NPC1RAB9AHTTNTSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226543-B1 | PROCESS FOR THE PREPARATION OF GLYCIDYL COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-09-29 | — | — | EP | claimed |
| US-4722983-A | REACTING A PHENOLIC COMPOUND WITH A HALOHYDRIN IN APROTIC SOLVENT | CIBA-GEIGY CORPORATION (US) | 1988-02-02 | — | — | US | claimed |
| US-4722983-A | REACTING A PHENOLIC COMPOUND WITH A HALOHYDRIN IN APROTIC SOLVENT | CIBA-GEIGY CORPORATION (US) | 1988-02-02 | — | — | US | disclosed |
| US-4722983-A | REACTING A PHENOLIC COMPOUND WITH A HALOHYDRIN IN APROTIC SOLVENT | CIBA-GEIGY CORPORATION (US) | 1988-02-02 | — | — | US | disclosed |