SCHEMBL9511292

SCHEMBL9511292

CCOc1cccc2c1Sc1ccccc1S2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.47
MAPT P10636 4/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 3/20 0.46
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 5/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GLA P06280 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
ALOX15 P16050 1/20 0.38
BRCA1 P38398 1/20 0.38
HBB P68871 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2786823 0.79 MCHR1 (0.42) GPR84MAPTHTTALDH1A1POLB
SCHEMBL32667391 0.79 CA1 (0.48) GPR84MAPTHTTALDH1A1L3MBTL1
SCHEMBL2417535 0.79 CA1 (0.48) GPR84MAPTHTTALDH1A1L3MBTL1
SCHEMBL10733167 0.78 GPR84 (0.43) GPR84MAPTHTTALDH1A1POLB
SCHEMBL29904981 0.74 NQO1 (0.42) MAPTALDH1A1TDP1LMNAGAA
SCHEMBL30716836 0.73 ALOX5 (0.39) MAPTPOLBCYP1A2TDP1MEN1
SCHEMBL12142036 0.72 GABRA1 (0.48) MAPTPOLBNPSR1GAABCHE
1,2-Diethoxybenzene SCHEMBL29428929 0.72 ALDH1A1 (0.68) MAPTALDH1A1L3MBTL1NPSR1GLA
1,2-Diethoxybenzene SCHEMBL578986 0.72 ALDH1A1 (0.68) MAPTALDH1A1L3MBTL1NPSR1GLA
SCHEMBL9507677 0.72 TSHR (0.41) HTTALDH1A1L3MBTL1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed