Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Oxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Oxide SCHEMBL7560 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL3993955 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL37670 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL5104249 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL7184108 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL2888647 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL306589 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL2731176 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL3636459 | 0.75 | — | — | |
| Nitric Oxide SCHEMBL2890900 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8092203-A | — | — | None | — | — | JP | disclosed |
| US-12037307-B2 | — | — | 2024-07-16 | — | — | US | disclosed |
| EP-4388876-A2 | FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES | FMC Corporation (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-112969688-B | Fungicidal nitroaniline-substituted pyrazoles | FMC公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3847160-B1 | FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES | FMC CORP (US) | 2024-05-08 | — | — | EP | disclosed |
| US-20230227400-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | API CORPORATION (JP) | 2023-07-20 | — | — | US | disclosed |
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| US-11643386-B2 | High purity 2-naphthylacetonitrile and method for producing same | API CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| EP-4118072-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION (US) | 2023-01-18 | — | — | EP | disclosed |
| CN-115605461-A | Fungicidal mixtures containing pyrazole derivatives | FMC公司（US） | 2023-01-13 | — | — | CN | disclosed |
| EP-1536784-A1 | HETERO BIARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| US-20040082639-A1 | N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-04-29 | — | — | US | disclosed |
| US-20040048863-A1 | Hetero biaryl derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY LLC | 2004-03-11 | — | — | US | disclosed |
| WO-2004014366-A1 | HETERO BIARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |
| US-6509361-B1 | Inhibit the activity of p38 MAP kinase. Also contemplated by the invention are processes for the preparation of the contemplated compounds and for the use of a contemplated compound in treating a mammalian host having a p38 kinase or | PHARMACIA CORPORATION | 2003-01-21 | — | — | US | disclosed |
| CN-2503363-Y | Spray thrower | WEI JINGCAI (CN) | 2002-07-31 | — | — | CN | disclosed |
| JP-H0892203-A | BATA-KETOTHIOAMIDE DERIVATIVE AND ITS PRODUCTION | AGENCY OF IND SCIENCE & TECHNOL | 1996-04-09 | — | — | JP | disclosed |
| US-5167834-A | PROCESS FOR TREATING NITRITE-AND SULFIDE-CONTAINING WATER TO REDUCE NITROGEN OXIDE AND HYDROGEN SULFIDE EMISSIONS THEREFROM | UNION OIL COMPANY OF CALIFORNIA (US) | 1992-12-01 | — | — | US | disclosed |