Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514091 | 0.78 | RAB9A (0.74) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL9512664 | 0.77 | RAB9A (0.78) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL13617010 | 0.77 | RAB9A (0.73) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL9513272 | 0.76 | RAB9A (0.76) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL9513301 | 0.75 | DRD2 (0.56) | DRD3KCNH2HRH1CHRM2ADRA2A | |
| SCHEMBL1704979 | 0.75 | RAB9A (0.74) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL3844538 | 0.74 | RAB9A (0.70) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| Hydrochloric Acid SCHEMBL1704951 | 0.74 | RAB9A (0.73) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL9514685 | 0.74 | RAB9A (1.00) | RAB9AGRIN2AGRIN2BTNKSPARP1 | |
| SCHEMBL7670965 | 0.73 | DRD3 (0.72) | DRD3KCNH2HRH1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334818-B1 | Pharmacologically active alkylthiobenz imidazole derivatives and process for the preparation thereof | DOMPE FARMACEUTICI SPA (IT) | 1993-12-01 | — | — | EP | disclosed |
| US-4983620-A | ANTIHISTAMINES, ANTIALLERGENS | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |