Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511594 | 0.81 | L3MBTL1 (0.60) | DRD2TBXA2RL3MBTL1MEN1KMT2A | |
| SCHEMBL4428203 | 0.76 | NPSR1 (0.58) | HRH1KCNH2CYP3A4MEN1KMT2A | |
| SCHEMBL9511640 | 0.75 | RAB9A (0.58) | DRD2TBXA2RHRH1OPRK1KCNH2 | |
| SCHEMBL588110 | 0.73 | KCNH2 (0.78) | DRD2TBXA2RHRH1OPRK1KCNH2 | |
| SCHEMBL3611802 | 0.73 | KCNH2 (0.78) | DRD2TBXA2RHRH1OPRK1KCNH2 | |
| SCHEMBL588111 | 0.73 | KCNH2 (0.78) | DRD2TBXA2RHRH1OPRK1KCNH2 | |
| SCHEMBL4435849 | 0.73 | HTR3A (0.67) | P2RX7HRH1KCNH2CYP2D6CHRM1 | |
| SCHEMBL8312716 | 0.73 | P2RX7 (0.71) | DRD2P2RX7HRH1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL587709 | 0.72 | LMNA (0.79) | DRD2TBXA2RHRH1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL588128 | 0.72 | LMNA (0.79) | DRD2TBXA2RHRH1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334818-B1 | Pharmacologically active alkylthiobenz imidazole derivatives and process for the preparation thereof | DOMPE FARMACEUTICI SPA (IT) | 1993-12-01 | — | — | EP | disclosed |
| US-4983620-A | ANTIHISTAMINES, ANTIALLERGENS | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |