Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733700 | 0.72 | PGK1 (0.35) | PGK1PGK2ARESR1ESR2 | |
| SCHEMBL1035151 | 0.70 | PGK1 (0.39) | PGK1PGK2 | |
| SCHEMBL9512151 | 0.69 | PGK1 (0.33) | PGK1PGK2 | |
| SCHEMBL11895632 | 0.68 | AR (0.35) | PGK1PGK2AR | |
| SCHEMBL7870277 | 0.68 | PGK1 (0.44) | PGK1PGK2ESR1ESR2 | |
| SCHEMBL11763736 | 0.68 | PGK1 (0.42) | PGK1PGK2 | |
| SCHEMBL11727886 | 0.68 | PGK1 (0.36) | CYP1A2CYP2D6PGK1PGK2AR | |
| SCHEMBL8936022 | 0.67 | PTPN5 (0.53) | — | |
| SCHEMBL9514388 | 0.67 | EGFR (0.34) | CYP1A2CYP2D6 | |
| SCHEMBL9512854 | 0.66 | PTPN5 (0.35) | PGK1PGK2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313002-B1 | Phenyl glycines for use in reducing neurotoxic injury | SEARLE & CO (US) | 1993-12-01 | — | — | EP | claimed |
| EP-0313002-A2 | Phenyl glycines for use in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0313002-B1 | Phenyl glycines for use in reducing neurotoxic injury | SEARLE & CO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-4918064-A | TREATMENT OF ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0313002-A2 | Phenyl glycines for use in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1989-04-26 | — | — | EP | disclosed |