Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731750 | 0.86 | PGK1 (0.40) | PGK1PGK2MEN1KMT2A | |
| SCHEMBL11727886 | 0.78 | PGK1 (0.36) | PGK1PGK2ESR1ARESR2 | |
| SCHEMBL11729784 | 0.78 | ESR1 (0.40) | PGK1PGK2HSD17B10MEN1KMT2A | |
| SCHEMBL11728190 | 0.75 | PGK1 (0.35) | PGK1PGK2MEN1KMT2A | |
| SCHEMBL9512171 | 0.72 | CYP1A2 (0.36) | PGK1PGK2ESR1ARESR2 | |
| SCHEMBL11731093 | 0.72 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL11757262 | 0.65 | PTPN1 (0.42) | ESR1ARESR2 | |
| SCHEMBL11760531 | 0.64 | PTPN1 (0.49) | PGK1PGK2ESR1ARESR2 | |
| SCHEMBL11728400 | 0.63 | PGK1 (0.41) | PGK1PGK2HSD17B10MEN1KMT2A | |
| SCHEMBL11730393 | 0.63 | PGK1 (0.41) | PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017455-A | Polyolefins and polyesters flame-proofed with carboxyalkyl and carbamoylalkyl substituted poly(phosphine oxides) | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-4009207-A | CARBAMOYLALKYL SUBSTITUTED POLY(PHOSPHINE OXIDE) FLAME-RETARDANTS | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3976685-A | Carboxyalkyl and carbamoylalkyl substituted poly(phosphine oxide) flame-retardants | AMERICAN CYANAMID COMPANY (US) | 1976-08-24 | — | — | US | disclosed |