Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 4/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532613 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDCDC25BHSD17B10 | |
| SCHEMBL10364551 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL5264765 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL5263528 | 0.81 | PLK1 (0.45) | ALDH1A1GAAGFERMKNK1MKNK2 | |
| SCHEMBL9513469 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EGAACDC25BHSD17B10 | |
| SCHEMBL7694710 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL5261951 | 0.79 | CA12 (0.47) | ALDH1A1KDM4EGAAMAPTHTT | |
| SCHEMBL1613338 | 0.74 | MMP2 (0.43) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL28885686 | 0.74 | BID (0.41) | KDM4EMAPTHSD17B10 | |
| SCHEMBL6118035 | 0.74 | CD44 (0.43) | ALDH1A1KDM4EGAAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | disclosed |