SCHEMBL9512604

SCHEMBL9512604

Clc1[c]ccc(-c2ccccc2Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
DPP4 P27487 1/20 0.39
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 2/20 0.36
HPGD P15428 1/20 0.36
PTPRC P08575 1/20 0.36
LMNA P02545 2/20 0.36
TSHR P16473 2/20 0.36
MAOB P27338 2/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
PLA2G7 Q13093 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HSD11B1 P28845 1/20 0.34
NOTUM Q6P988 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1978535 0.80 NPC1 (0.37) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL10743684 0.80 PTPRC (0.33) NPC1PTPRCPOLBKMT2AALDH1A1
SCHEMBL7455214 0.80 POLB (0.41) CYP2A6DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL456349 0.78 CYP2A6 (0.44) CYP2A6DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL6207069 0.77 CYP2A6 (0.43) CYP2A6NPC1RAB9AHPGDLMNA
SCHEMBL11815058 0.76 HSD11B1 (0.39) HPGDTSHRALDH1A1HSD11B1NOTUM
SCHEMBL10589634 0.75 CYP2A6 (0.41) CYP2A6DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL9729126 0.75 CYP2A6 (0.41) CYP2A6DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL671133 0.74 CYP2A6 (0.67) CYP2A6DPP4NPC1RAB9ASMN1; SMN2
SCHEMBL29883244 0.74 CYP2A6 (0.67) CYP2A6DPP4NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US claimed
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 WO disclosed
EP-0341825-B1 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 1993-11-18 EP disclosed
EP-0333415-B1 AN ELECTROPHOTOGRAPHIC LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 1993-09-22 EP disclosed
US-5053301-A Zinc oxide, resin binder, hydrophilic resin grains FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
US-4971870-A OFFSET PRINTING, ELECTROCONDUCTORS, PHOTOCONDUCTORS, BINDER RESINS, MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1990-11-20 US disclosed
EP-0341825-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1989-11-15 EP disclosed
EP-0333415-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed