Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618651 | 0.81 | MYC (0.34) | CYP1A2CA1CA2CA9HTR7 | |
| SCHEMBL9512604 | 0.80 | CYP2A6 (0.41) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL6226779 | 0.80 | NPC1 (0.39) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL10743684 | 0.77 | PTPRC (0.33) | NPC1MEN1KMT2AALDH1A1NOTUM | |
| SCHEMBL1982913 | 0.76 | PLA2G7 (0.36) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL16934082 | 0.74 | TSHR (0.43) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL6207069 | 0.74 | CYP2A6 (0.43) | NPC1RAB9AHPGDHSD17B10CYP1A2 | |
| SCHEMBL11028217 | 0.73 | TRPA1 (0.34) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL9804899 | 0.73 | NPC1 (0.34) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL11815058 | 0.73 | HSD11B1 (0.39) | TSHRHPGDHSD17B10CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |