Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512749 | 0.88 | CA5A (0.52) | CA5ACTSKCTSLSPPL2APSMB1 | |
| SCHEMBL9509406 | 0.88 | CA5A (0.52) | CA5ACTSKCTSLSPPL2APSMB1 | |
| SCHEMBL9509435 | 0.88 | MME (0.54) | CA5ACTSKCTSLPSMB1CAPN1 | |
| SCHEMBL10589458 | 0.86 | MME (0.51) | CA5ACTSKCTSLPSMB1CAPN1 | |
| SCHEMBL9512806 | 0.85 | SPPL2A (0.51) | CA5ACTSKCTSLSPPL2ACYP1A2 | |
| SCHEMBL9499472 | 0.83 | TRPM8 (0.53) | CA5ACTSKCTSLSPPL2ACYP1A2 | |
| SCHEMBL9502253 | 0.83 | TRPM8 (0.53) | CA5ACTSKCTSLSPPL2ACYP1A2 | |
| SCHEMBL9499470 | 0.83 | TRPM8 (0.53) | CA5ACTSKCTSLSPPL2ACYP1A2 | |
| SCHEMBL9633578 | 0.82 | TRPM8 (0.52) | CA5ACTSKCTSLSPPL2ACYP1A2 | |
| SCHEMBL9632870 | 0.81 | CTRB1 (0.60) | CA5ACTSKCTSLCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332999-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| US-5028626-A | Peptides with pharmaceutical activity | ZAMBON GROUP S.P.A. (IT) | 1991-07-02 | — | — | US | disclosed |
| EP-0332999-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |