Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901403 | 1.00 | TP53 (0.34) | TP53ALDH1A1HTTRXRAAKR1C3 | |
| SCHEMBL6902528 | 0.93 | ADH1B (0.35) | TP53ALDH1A1HTT | |
| SCHEMBL6902527 | 0.93 | ADH1B (0.35) | TP53ALDH1A1HTT | |
| SCHEMBL812178 | 0.89 | ALDH1A1 (0.34) | ALDH1A1HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL809609 | 0.89 | ALDH1A1 (0.34) | ALDH1A1HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL9512837 | 0.86 | NPC1 (0.33) | ALDH1A1HTTKMT2A | |
| SCHEMBL6900658 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL1077341 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL18186752 | 0.78 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL18186751 | 0.78 | SMN1; SMN2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833481-B2 | Catalytic dehydrative isomerization | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-12-21 | — | — | US | disclosed |
| US-20030109755-A1 | Process for producing 2-alkyl-2cyclopentenones | TAKASAGO INTERNATIONAL CORPORATION | 2003-06-12 | — | — | US | disclosed |
| EP-1316541-A1 | Process for producing 2-alkyl-2-cyclopentenones | Takasago International Corporation (JP) | 2003-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109755-A1 | Process for producing 2-alkyl-2cyclopentenones | HSD3B2, DHPS, HSD3B1 | TP53 4182/4885ALDH1A1 575/4885HTT 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.