SCHEMBL9512954

SCHEMBL9512954

COc1ccc(NNC=O)cc1CCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.40
▸ HTR6 P50406 1/20 0.40
▸ PPARD Q03181 1/20 0.40
▸ PPARA Q07869 1/20 0.40
▸ KDM1A O60341 1/20 0.40
▸ ITGB3 P05106 1/20 0.40
▸ ITGAV P06756 1/20 0.40
▸ ITGA2B P08514 1/20 0.40
▸ BRD4 O60885 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ FFAR1 O14842 2/20 0.39
▸ SLC13A5 Q86YT5 1/20 0.38
▸ FFAR4 Q5NUL3 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11366139 0.81 HTR6 (0.46) POLBHSD17B10HTR6PPARDPPARA
SCHEMBL11209886 0.79 RAB9A (0.39) HTR6BRD4NPC1RAB9A
SCHEMBL11376820 0.76 ALDH1A1 (0.50) POLBHSD17B10HPGDFFAR1SLC13A5
SCHEMBL30873972 0.74 SLC13A5 (0.62) POLBHSD17B10HPGDFFAR1SLC13A5
SCHEMBL1209727 0.74 SLC13A5 (0.62) POLBHSD17B10HPGDFFAR1SLC13A5
SCHEMBL30436820 0.74 HSD17B10 (0.71) POLBHSD17B10
SCHEMBL491188 0.74 HSD17B10 (0.71) POLBHSD17B10
SCHEMBL7827237 0.73 NPSR1 (0.55) POLBHSD17B10FFAR1FFAR4
SCHEMBL7433243 0.73 FFAR1 (0.50) POLBHSD17B10FFAR1
SCHEMBL7994543 0.73 KDM4E (0.55) POLBHSD17B10FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301799-B1 Photographic high contrast silver halide elements and process using them EASTMAN KODAK CO (US) 1993-11-24 — — EP disclosed
EP-0301799-A2 Photographic high contrast silver halide elements and process using them EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-02-01 — — EP disclosed
US-4278748-A Absorbed hydrazide nucleating agents and photographic elements containing such agents EASTMAN KODAK COMPANY (US) 1981-07-14 — — US disclosed
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