Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589370 | 0.87 | MEN1 (0.63) | MEN1MAPTKMT2A | |
| SCHEMBL13328416 | 0.81 | MEN1 (0.65) | SMN1; SMN2MEN1MAPTKMT2ALMNA | |
| SCHEMBL9513684 | 0.80 | EPHX1 (0.63) | MEN1MAPTKMT2AEPHX1 | |
| SCHEMBL9514663 | 0.80 | CES2 (0.62) | SMN1; SMN2EPHX1 | |
| SCHEMBL9359527 | 0.79 | LPAR1 (0.49) | MTNR1ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2608948 | 0.78 | MTNR1A (0.68) | MTNR1AKMT2AMTNR1B | |
| SCHEMBL9131472 | 0.77 | MTNR1A (0.76) | MTNR1ACA12CA1CA2CA9 | |
| SCHEMBL6688137 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2ALMNA | |
| SCHEMBL2692928 | 0.76 | MTNR1A (0.73) | MTNR1ACA12CA1CA2CA9 | |
| SCHEMBL9514688 | 0.75 | KDM4E (0.61) | SMN1; SMN2EPHX2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | disclosed |