Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513684 | 0.85 | EPHX1 (0.63) | EPHX1 | |
| SCHEMBL9513440 | 0.80 | MTNR1A (0.64) | SMN1; SMN2EPHX1 | |
| SCHEMBL9514688 | 0.78 | KDM4E (0.61) | SMN1; SMN2EPHX1 | |
| SCHEMBL17040271 | 0.77 | CES2 (0.61) | CES2 | |
| SCHEMBL4433152 | 0.77 | CES2 (1.00) | CES2 | |
| SCHEMBL30192907 | 0.77 | CES2 (1.00) | CES2 | |
| SCHEMBL6688137 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2 | |
| SCHEMBL761158 | 0.75 | KDM4E (0.61) | CES2SMN1; SMN2 | |
| SCHEMBL17037431 | 0.75 | CES2 (0.58) | CES2 | |
| SCHEMBL2732841 | 0.73 | CYP1A2 (0.58) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | disclosed |