Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | UQCRB | P14927 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765326 | 0.86 | GRIA4 (0.63) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL9512068 | 0.79 | TBXA2R (0.63) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL29554998 | 0.76 | TP53 (0.55) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL28404275 | 0.75 | GBA1 (0.61) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL4986251 | 0.75 | GBA1 (1.00) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL12949528 | 0.73 | GBA1 (0.58) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL29555017 | 0.73 | MAPT (0.52) | GBA1MAPTTP53KMT2AMEN1 | |
| SCHEMBL174302 | 0.73 | GBA1 (0.57) | GBA1MAPTTP53KMT2AGRIA4 | |
| SCHEMBL28023600 | 0.73 | ALDH1A1 (0.67) | GBA1KMT2AMEN1GAALMNA | |
| SCHEMBL13508355 | 0.73 | GBA1 (0.57) | GBA1MAPTTP53KMT2AGRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0325245-A1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |