Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 5/20 | 0.63 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | UQCRB | P14927 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513595 | 0.86 | GBA1 (0.59) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL10448426 | 0.84 | GRIA4 (0.63) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL10448368 | 0.80 | KMT2A (0.58) | GRIA4GBA1MAPTKMT2ALMNA | |
| SCHEMBL28023600 | 0.78 | ALDH1A1 (0.67) | GBA1KMT2ALMNAMEN1 | |
| SCHEMBL174302 | 0.78 | GBA1 (0.57) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL13508355 | 0.78 | GBA1 (0.57) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL6179006 | 0.78 | GRIA4 (0.56) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL27287741 | 0.78 | GRIA4 (0.56) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL674105 | 0.78 | ALDH1A1 (0.66) | GRIA4GBA1TP53MAPTKMT2A | |
| SCHEMBL5878210 | 0.77 | GRIA4 (1.00) | GRIA4GBA1TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |