Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | UQCRB | P14927 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765329 | 0.85 | MEN1 (0.51) | ESR2ALDH1A1ESR1CYP3A4MEN1 | |
| SCHEMBL9512076 | 0.78 | TBXA2R (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL6903823 | 0.75 | NR3C2 (0.53) | ALDH1A1MEN1KMT2ACYP2C19NR3C2 | |
| SCHEMBL9707019 | 0.75 | ALDH1A1 (0.49) | ALDH1A1ESR1MEN1KMT2ACYP2C19 | |
| SCHEMBL28404277 | 0.73 | CYP2C19 (0.51) | ALDH1A1KMT2ACYP2C19NR3C2CYTH2 | |
| SCHEMBL1479992 | 0.73 | ALDH1A1 (0.59) | ALDH1A1CYP3A4MEN1KMT2AUQCRB | |
| SCHEMBL349527 | 0.73 | MAPT (0.66) | ALDH1A1CYP3A4MEN1KMT2ACYP2C19 | |
| Bisphenol A SCHEMBL10477991 | 0.73 | ESR2 (0.68) | ESR2ALDH1A1ESR1CYP3A4MEN1 | |
| SCHEMBL1479993 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KMT2ACYP2C19SMN1; SMN2CA1 | |
| SCHEMBL7984128 | 0.72 | BLM (0.48) | ALDH1A1ESR1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0325245-A1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |