Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | UQCRB | P14927 | 3/20 | 0.50 |
| ▸ | DUT | P33316 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.45 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903823 | 0.88 | NR3C2 (0.53) | MEN1KMT2ADUTALDH1A1CYP2C19 | |
| SCHEMBL15199347 | 0.85 | UQCRB (0.53) | MEN1KMT2AUQCRBALDH1A1CYTH2 | |
| SCHEMBL9513604 | 0.85 | ESR2 (0.50) | MEN1KMT2AUQCRBESR2ESR1 | |
| SCHEMBL10448561 | 0.83 | KEAP1 (0.53) | MEN1KMT2ADUTALDH1A1CYP3A4 | |
| SCHEMBL21690373 | 0.80 | DUT (0.56) | DUTALDH1A1CYP2C19NR3C2NAMPT | |
| SCHEMBL1409455 | 0.80 | DUT (0.56) | DUTALDH1A1CYP2C19NR3C2NAMPT | |
| SCHEMBL10448367 | 0.78 | CA2 (0.55) | MEN1KMT2ADUTALDH1A1NR3C2 | |
| SCHEMBL18726029 | 0.78 | CA12 (0.54) | MEN1KMT2AALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL27827531 | 0.77 | DUT (0.54) | MEN1KMT2ADUTALDH1A1CYP2C19 | |
| SCHEMBL9707019 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2AESR1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |