Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763736 | 0.73 | PGK1 (0.42) | PGK1PGK2ALDH1A1 | |
| SCHEMBL11761874 | 0.70 | PTPN1 (0.36) | PGK1PGK2 | |
| SCHEMBL26908623 | 0.69 | ALDH1A1 (0.40) | SRCALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL11730393 | 0.69 | PGK1 (0.41) | PGK1PGK2 | |
| SCHEMBL9512151 | 0.69 | PGK1 (0.33) | PGK1PGK2 | |
| SCHEMBL6298903 | 0.69 | PGK1 (0.34) | PGK1PGK2 | |
| SCHEMBL2884919 | 0.69 | GRIA1 (0.56) | SRCALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL1035151 | 0.68 | PGK1 (0.39) | PGK1PGK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9172802 | 0.67 | PGK1 (0.37) | PGK1PGK2 | |
| SCHEMBL1585204 | 0.66 | TSHR (0.41) | PGK1PGK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313002-B1 | Phenyl glycines for use in reducing neurotoxic injury | SEARLE & CO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-4918064-A | TREATMENT OF ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0313002-A2 | Phenyl glycines for use in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1989-04-26 | — | — | EP | disclosed |