Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 4/20 | 0.41 |
| ▸ | PGK2 | P07205 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728400 | 0.86 | PGK1 (0.41) | PGK1PGK2CYP1A2CYP2D6 | |
| SCHEMBL11727886 | 0.86 | PGK1 (0.36) | PGK1PGK2CYP1A2CYP2D6 | |
| SCHEMBL11729751 | 0.83 | KDM4E (0.31) | PGK1PGK2 | |
| SCHEMBL11727825 | 0.80 | PGK1 (0.36) | PGK1PGK2 | |
| SCHEMBL11726065 | 0.77 | FDPS (0.32) | — | |
| SCHEMBL11731750 | 0.75 | PGK1 (0.40) | PGK1PGK2 | |
| SCHEMBL11729784 | 0.73 | ESR1 (0.40) | PGK1PGK2CYP1A2CYP2D6 | |
| SCHEMBL9514039 | 0.69 | PGK1 (0.38) | PGK1PGK2 | |
| SCHEMBL11724415 | 0.67 | NPSR1 (0.37) | PGK1PGK2 | |
| SCHEMBL11764065 | 0.66 | FDPS (0.46) | PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017455-A | Polyolefins and polyesters flame-proofed with carboxyalkyl and carbamoylalkyl substituted poly(phosphine oxides) | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-4009207-A | CARBAMOYLALKYL SUBSTITUTED POLY(PHOSPHINE OXIDE) FLAME-RETARDANTS | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3976685-A | Carboxyalkyl and carbamoylalkyl substituted poly(phosphine oxide) flame-retardants | AMERICAN CYANAMID COMPANY (US) | 1976-08-24 | — | — | US | disclosed |