Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TLR4 | O00206 | 3/20 | 0.35 |
| ▸ | TLR2 | O60603 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514304 | 1.00 | ALB (0.44) | ALBCYSLTR2CYSLTR1FBP1KDM4E | |
| SCHEMBL9515927 | 0.89 | ALB (0.49) | ALBCYSLTR2CYSLTR1KDM4ESMN1; SMN2 | |
| SCHEMBL9515938 | 0.89 | ALB (0.49) | ALBCYSLTR2CYSLTR1KDM4ESMN1; SMN2 | |
| SCHEMBL5778529 | 0.73 | ALB (0.58) | ALBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL5775275 | 0.71 | ALB (0.52) | ALBCYSLTR2CYSLTR1FBP1 | |
| SCHEMBL5780145 | 0.70 | ALB (0.48) | ALBKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5779807 | 0.70 | ALB (0.61) | ALBFBP1 | |
| SCHEMBL5774563 | 0.69 | ALB (0.69) | ALBKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8304425 | 0.69 | ALB (0.52) | ALBKDM4ESMN1; SMN2ALDH1A1APP | |
| SCHEMBL5775071 | 0.69 | ALB (0.60) | ALBKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |