Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515927 | 1.00 | ALB (0.49) | ALBPPARAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9514304 | 0.89 | ALB (0.44) | ALBPPARAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9514296 | 0.89 | ALB (0.44) | ALBPPARAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5779807 | 0.74 | ALB (0.61) | ALB | |
| SCHEMBL5775275 | 0.74 | ALB (0.52) | ALBCYSLTR2CYSLTR1MEN1ADORA3 | |
| SCHEMBL11091440 | 0.72 | PPARA (0.60) | PPARAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5774563 | 0.72 | ALB (0.69) | ALBKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL8304428 | 0.72 | ALB (0.52) | ALBKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8304425 | 0.72 | ALB (0.52) | ALBKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5775071 | 0.71 | ALB (0.60) | ALBKDM4EALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |