SCHEMBL95144

SCHEMBL95144

[CH2]CCC=Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.48
IDO1 P14902 2/20 0.48
PAM P19021 1/20 0.48
MAOB P27338 2/20 0.46
HTR2A P28223 3/20 0.45
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95143 1.00 SIGMAR1 (0.48) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL1532665 0.89 IDO1 (0.44) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL96607 0.86 SIGMAR1 (0.46) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL96606 0.86 SIGMAR1 (0.46) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL7939387 0.85 IDO1 (0.56) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL7568412 0.85 IDO1 (0.56) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL10430031 0.85 IDO1 (0.56) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL21178175 0.85 SIGMAR1 (0.44) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL1003495 0.83 SIGMAR1 (0.43) SIGMAR1IDO1PAMMAOBHTR2A
SCHEMBL542493 0.83 SIGMAR1 (0.43) SIGMAR1IDO1PAMMAOBHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118308007-A Ocean antifouling paint with piezoelectric conductivity and preparation and application thereof 武汉理工大学三亚科教创新园 2024-07-09 CN claimed
CN-118185421-A Piezoelectric semiconductor composite coating based on silicon dioxide, preparation method and application 武汉理工大学 2024-06-14 CN claimed
CN-116161896-A Antistatic sound absorbing material, preparation method thereof, loudspeaker and electronic equipment 镇江贝斯特新材料股份有限公司 2023-05-26 CN claimed
CN-112280245-A Resin composition, prepreg, metal-clad laminate, and circuit board 苏州生益科技有限公司 2021-01-29 CN claimed
CN-108004789-B A kind of preparation method of electrochromism liquid crystal microcapsule used for textiles 江南大学 2019-06-07 CN claimed
CN-108004789-A A kind of preparation method of electrochromism liquid crystal microcapsule used for textiles 江南大学 2018-05-08 CN claimed
EP-0205834-B1 7-THIABICYCLOHEPTANE SUBSTITUTED ETHERS E.R. Squibb & Sons, Inc. (US) 1990-10-31 EP claimed
CN-118222209-A Black optical film, cured film and application thereof 杭州福斯特电子材料有限公司 2024-06-21 CN disclosed
CN-118185421-A Piezoelectric semiconductor composite coating based on silicon dioxide, preparation method and application 武汉理工大学 2024-06-14 CN disclosed
US-11273168-B2 Methods of treating anxiety by administering a substituted quinolone OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-03-15 US disclosed
US-11254832-B2 Fluid sets HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-02-22 US disclosed
CN-112280245-A Resin composition, prepreg, metal-clad laminate, and circuit board 苏州生益科技有限公司 2021-01-29 CN disclosed
US-20200308436-A1 FLUID SETS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-10-01 US disclosed
US-4845100-A WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-04 US disclosed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 CN disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed
EP-0255134-A2 Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-02-03 EP disclosed
EP-0202760-A2 Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-11-26 EP disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11273168-B2 Methods of treating anxiety by administering a substituted quinolone CRH, MC2R, HTR3C SIGMAR1 310/4885IDO1 747/4885PAM 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.