SCHEMBL951446

SCHEMBL951446

CC(C)(C)C1CCC(OC(=O)C2CC3C=CC2C3)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
CYP19A1 P11511 1/20 0.39
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 3/20 0.37
KMT2A Q03164 3/20 0.37
HTT P42858 1/20 0.37
GAA P10253 1/20 0.36
APEX1 P27695 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
ESR2 Q92731 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3365931 0.82 LMNA (0.47) MAPTKDM4ELMNAALDH1A1HPGD
SCHEMBL13888469 0.81 KDM4E (0.44) KDM4ELMNAALDH1A1HPGDRAB9A
SCHEMBL28630522 0.80 LMNA (0.46) MAPTKDM4ELMNAALDH1A1HPGD
SCHEMBL20375290 0.80 LMNA (0.46) MAPTKDM4ELMNAALDH1A1HPGD
SCHEMBL947840 0.80 LMNA (0.46) MAPTKDM4ELMNAALDH1A1HPGD
SCHEMBL11908671 0.80 LMNA (0.46) MAPTKDM4ELMNAALDH1A1HPGD
SCHEMBL3367480 0.79 MAPT (0.46) MAPTKDM4ELMNACYP19A1APOBEC3A
SCHEMBL22263842 0.79 KDM4E (0.37) KDM4ELMNAALDH1A1HPGDRAB9A
SCHEMBL12228727 0.79 NAAA (0.41) MAPTKDM4ELMNAALDH1A1HPGD
SCHEMBL2135609 0.78 KDM4E (0.44) KDM4ELMNAALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8609574-B2 In situ olefin polymerization catalyst system PROMERUS LLC (US) 2013-12-17 US disclosed
EP-2296811-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM Promerus, LLC (US) 2011-03-23 EP disclosed
US-7910674-B2 Especially a copolymer of norbornene and/or alkylnorbornene and (trialkoxysilylalkyl)norbornene; optical articles such as ophthalmic lenses, wave guides, optical fibers, and optical adhesives PROMERUS, LLC (US) 2011-03-22 US disclosed
US-7875686-B2 comprising 10 to 99 wt. % of norbornene-type cycloolefin monomers; for microelectronic, optoelectronic and micro-optoelectronic applications such as die attach adhesives, underfill materials, prepreg binders, encapsulants PROMERUS LLC (US) 2011-01-25 US disclosed
EP-1164434-B1 Radiation-sensitive resin composition JSR CORP (JP) 2010-10-06 EP disclosed
EP-1270553-B1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORP (JP) 2009-11-18 EP disclosed
US-20090270247-A1 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 US disclosed
WO-2009132240-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 WO disclosed
EP-1791888-B1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS PROMERUS LLC (US) 2009-03-25 EP disclosed
US-7314701-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2008-01-01 US disclosed
EP-1048983-A1 Radiation sensitive resin composition JSR Corporation (JP) 2000-11-02 EP disclosed
EP-1034196-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-09-13 EP disclosed
WO-2000020472-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-04-13 WO disclosed
EP-0930541-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-07-21 EP disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0409291-B1 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-02-14 EP disclosed
EP-0317262-B1 Transparent resin material JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-01-31 EP disclosed
US-5053471-A Methathesis ring opening polymerization of polar substituted norbornenes or octahydromethanonphthalenes; optics JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-10-01 US disclosed
EP-0409291-A2 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-23 EP disclosed