Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ATR | Q13535 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | TARBP2 | Q15633 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514705 | 0.88 | TARBP2 (0.64) | GSK3BMEN1KMT2AATRHTT | |
| SCHEMBL9329569 | 0.86 | PKM (0.46) | GSK3BMEN1KMT2AATRHTT | |
| SCHEMBL4299733 | 0.81 | PKM (0.60) | POLBCYP3A4ALDH1A1MAPTPKM | |
| SCHEMBL9515570 | 0.79 | TARBP2 (0.73) | GSK3BMEN1KMT2AATRHTT | |
| SCHEMBL18489995 | 0.79 | PKM (0.48) | MEN1KMT2APOLBCYP3A4CDK2 | |
| SCHEMBL9329600 | 0.78 | CYP3A4 (0.40) | GSK3BMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL10615868 | 0.77 | TARBP2 (0.44) | GSK3BMEN1KMT2AATRHTT | |
| SCHEMBL9094972 | 0.77 | LCK (0.46) | MEN1KMT2APOLBCYP3A4CDK2 | |
| SCHEMBL17714986 | 0.77 | TARBP2 (0.70) | GSK3BMEN1KMT2AATRHTT | |
| SCHEMBL1368787 | 0.76 | CYP3A4 (0.51) | MEN1KMT2APOLBCYP3A4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269754-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5032685-A | Hepatitis | TSUMURA JUNTENDO, INC. (JP) | 1991-07-16 | — | — | US | disclosed |
| US-4987240-A | PREFERENTIAL DEHALOGENATION OF CHEMICAL INTERMEDIATE | TSUMURA & CO. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4962211-A | MODERATING ACTION ON LIVER DISORDERS; CHEMICAL INTERMEDIATES; ACUTE AND CHRONIC HEPATITIS | TSUMURA & CO. (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4904694-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-02-27 | — | — | US | disclosed |