Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
| ▸ | MPI | P34949 | 2/20 | 0.44 |
| ▸ | PMM2 | O15305 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 10/20 | 0.41 |
| ▸ | RGS4 | P49798 | 1/20 | 0.41 |
| ▸ | RGS8 | P57771 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132283 | 0.78 | MIF (0.46) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL11100610 | 0.70 | RAB9A (0.54) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL8426763 | 0.70 | MEN1 (1.00) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL7624622 | 0.67 | KAT2B (0.64) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL1533692 | 0.65 | MEN1 (0.68) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL17131812 | 0.64 | MIF (0.69) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL10552329 | 0.62 | ALDH1A1 (0.49) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL7623894 | 0.62 | KAT2B (0.67) | KAT2BMEN1MAPTRAB9AKMT2A | |
| SCHEMBL8371770 | 0.61 | MIF (0.77) | KAT2BMPIPMM2G6PDMIF | |
| SCHEMBL2537846 | 0.61 | MPI (1.00) | MAPTRAB9AALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5151447-A | Bactericides and fungicides | ROHM AND HAAS COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5023275-A | S-substituted beta-thioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |