Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707261 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1RAB9ALMNAMAPT | |
| SCHEMBL20543639 | 0.78 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRRAB9ALMNA | |
| SCHEMBL11531232 | 0.78 | LMNA (0.45) | ALDH1A1TSHRRAB9ALMNAMAPT | |
| SCHEMBL9510197 | 0.77 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1RAB9ALMNAMAPT | |
| SCHEMBL1965496 | 0.76 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TSHRRAB9ALMNA | |
| Ethyl Acetate SCHEMBL9737551 | 0.73 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TSHRRAB9ALMNA | |
| SCHEMBL25075052 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TSHRRAB9ALMNAMAPT | |
| SCHEMBL16768106 | 0.72 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRRAB9ALMNA | |
| SCHEMBL27617691 | 0.72 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRKMT2ANPSR1 | |
| SCHEMBL25075051 | 0.72 | HRH3 (0.38) | ALDH1A1TSHRRAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |