Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566746 | 0.84 | ALDH1A1 (0.38) | KMT2AMAPTCCNCCDK8PPARA | |
| SCHEMBL9519559 | 0.82 | P4HTM (0.49) | KMT2APPARAPPARGP4HTMLMNA | |
| SCHEMBL9319775 | 0.78 | PDE10A (0.39) | KMT2AMAPTPPARAALDH1A1PPARG | |
| SCHEMBL9515534 | 0.78 | MAPT (0.58) | MAPTALDH1A1P4HTMHPGDCYP1A2 | |
| SCHEMBL9515811 | 0.77 | P4HTM (0.35) | KMT2AMAPTCCNCCDK8ACACB | |
| SCHEMBL9319319 | 0.77 | P4HTM (0.35) | KMT2AMAPTCCNCCDK8ACACB | |
| SCHEMBL10817490 | 0.77 | GABRP (0.40) | KMT2AMAPTALDH1A1P4HTMFFAR1 | |
| SCHEMBL18961357 | 0.76 | MAPT (0.44) | MAPTNPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9566853 | 0.76 | CYSLTR2 (0.32) | KMT2AMAPTCCNCCDK8ACACB | |
| Ether SCHEMBL9580541 | 0.75 | ELANE (0.47) | KMT2AMAPTALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |