Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.57 |
| ▸ | ATP4A | P20648 | 16/20 | 0.49 |
| ▸ | ATP4B | P51164 | 16/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518053 | 1.00 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1ATP4AATP4BKDM4E | |
| SCHEMBL9516834 | 0.85 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1ATP4AATP4BKDM4E | |
| SCHEMBL9516841 | 0.85 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1ATP4AATP4BKDM4E | |
| SCHEMBL9515581 | 0.84 | ATP4A (0.55) | ATP4AATP4B | |
| SCHEMBL9515591 | 0.84 | ATP4A (0.55) | ATP4AATP4B | |
| SCHEMBL22472257 | 0.84 | MEN1 (0.53) | ATP4AATP4BKDM4EMEN1ALDH1A1 | |
| SCHEMBL9515993 | 0.81 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1ATP4AATP4BKDM4E | |
| SCHEMBL9515980 | 0.81 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1ATP4AATP4BKDM4E | |
| SCHEMBL10720978 | 0.77 | ALOX5 (0.48) | KDM4ELMNAGLO1MEN1ALDH1A1 | |
| SCHEMBL9514441 | 0.77 | POLB (0.56) | KDM4ELMNAMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |