Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC6A15 | Q9H2J7 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515147 | 0.79 | DRD2 (0.47) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Fumaric Acid SCHEMBL9517664 | 0.77 | HRH2 (0.53) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Maleic Acid SCHEMBL9517655 | 0.77 | HRH2 (0.53) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9515621 | 0.74 | CYP2D6 (0.51) | ALDH1A1TSHRHRH1NPC1CYP2D6 | |
| Fumaric Acid SCHEMBL9516875 | 0.74 | CYP2D6 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL12065129 | 0.73 | HRH1 (0.61) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL1295044 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL11576671 | 0.73 | POLB (0.50) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL9272255 | 0.73 | PTGER1 (0.54) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL13870466 | 0.72 | SLC6A15 (0.62) | ALDH1A1MEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423870-B1 | DIBENZODIOXAZECINE AND DIBENZODIOXAAZACYCLOUNDECINE DERIVATIVES | Akzo Nobel N.V. (NL) | 1993-07-14 | — | — | EP | disclosed |
| US-5106839-A | DIBENZODIOXAZECINE AND DIBENZODIOXAAZACYCLOUNDECINE DERIVATIVES | AKZO N.V. (NL) | 1992-04-21 | — | — | US | disclosed |
| EP-0423870-A1 | Dibenzodioxazecine and dibenzodioxaazacycloundecine derivatives | Akzo Nobel N.V. (NL) | 1991-04-24 | — | — | EP | disclosed |