Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519628 | 0.92 | BCL2L1 (0.42) | BCL2L1MCL1NPC1RAB9AP4HTM | |
| SCHEMBL9517937 | 0.89 | EGFR (0.40) | NPC1RAB9AP4HTMCASP3EGFR | |
| SCHEMBL9516087 | 0.88 | BCL2L1 (0.38) | BCL2L1MCL1P4HTMCASP3CXCR2 | |
| SCHEMBL9517259 | 0.84 | EGFR (0.39) | P4HTMCASP3EGFRSMN1; SMN2SCN5A | |
| SCHEMBL9516974 | 0.83 | EGFR (0.44) | NPC1RAB9AP4HTMCASP3EGFR | |
| SCHEMBL9517165 | 0.83 | VNN1 (0.40) | BCL2L1MCL1SCN9AHDAC6 | |
| SCHEMBL9515738 | 0.82 | P4HTM (0.43) | BCL2L1MCL1NPC1RAB9AP4HTM | |
| SCHEMBL9516990 | 0.80 | P4HTM (0.37) | P4HTMCASP3EGFRSCN5ASCN9A | |
| SCHEMBL9517908 | 0.79 | CXCR1 (0.39) | P4HTMCASP3CXCR2HDAC6 | |
| SCHEMBL9517088 | 0.78 | CXCR2 (0.38) | BCL2L1MCL1P4HTMCASP3CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |